Prices as of 2026/10/30 close
Company comparison · OTC & Skin-Care Medicines
Rohto is the largest by revenue at ¥343.7B, followed by Santen (¥291.6B), Kobayashi (¥165.7B) and Zeria (¥89.2B).
Santen has the highest operating margin at 16.4%, 7.4 points above the lowest, Kobayashi (9.0%).
Revenue growth in the latest results: Rohto +11.4%, Zeria +2.1%, Kobayashi +0.1%, Santen −2.8%. For next year, Rohto guides for the fastest operating profit growth (+6.5%).
Santen pays the most on average (¥9.02M), ¥1.45M more than Kobayashi (¥7.57M).
Over the past year the shares moved Kobayashi +39.5%, Santen +21.9%, Rohto +16.3%, Zeria +1.1%.
Head-to-head wins18 metrics
One win per metric for the company with the best value. Metrics with no better or worse (P/E, average age, employees) are excluded.
ScaleInvestors
Santen aheadRohto 1 : Santen 2 : Kobayashi 0 : Zeria 0
Revenue: Rohto ¥343.7B / Santen ¥291.6B / Kobayashi ¥165.7B / Zeria ¥89.2B
ProfitabilityInvestors
Santen aheadRohto 1 : Santen 3 : Kobayashi 0 : Zeria 0
Operating margin: Rohto 12.0% / Santen 16.4% / Kobayashi 9.0% / Zeria 13.9%
GrowthInvestors
Rohto aheadRohto 5 : Santen 0 : Kobayashi 0 : Zeria 0
Revenue growth (YoY): Rohto +11.4% / Santen −2.8% / Kobayashi +0.1% / Zeria +2.1%
Stock & balance sheetInvestors
Kobayashi aheadRohto 0 : Santen 0 : Kobayashi 3 : Zeria 0
Share price, 1 year: Rohto +16.3% / Santen +21.9% / Kobayashi +39.5% / Zeria +1.1%
Pay & workforceJob seekers
Santen aheadRohto 0 : Santen 2 : Kobayashi 0 : Zeria 1
Average salary: Rohto ¥8.26M / Santen ¥9.02M / Kobayashi ¥7.57M / Zeria ¥7.99M
| Metric | Rohto | Santen | Kobayashi | Zeria |
|---|---|---|---|---|
| Revenue | ◎¥343.7B | ¥291.6B | ¥165.7B | ¥89.2B |
| Operating profit | ¥41.1B | ◎¥47.8B | ¥14.9B | ¥12.4B |
| Net income | ¥34.2B | ◎¥37.4B | ¥3.7B | ¥8.5B |
| Metric | Rohto | Santen | Kobayashi | Zeria |
|---|---|---|---|---|
| Operating margin | 12.0% | ◎16.4% | 9.0% | 13.9% |
| Net margin | 10.0% | ◎12.8% | 2.2% | 9.5% |
| ROE | — | ◎12.8% | 1.7% | 8.5% |
| Revenue per employee | ◎¥196M | ¥155M | ¥100M | ¥102M |
| Metric | Rohto | Santen | Kobayashi | Zeria |
|---|---|---|---|---|
| Revenue growth (YoY) | ◎+11.4% | −2.8% | +0.1% | +2.1% |
| Operating profit growth (YoY) | ◎+7.5% | +2.0% | −40.0% | +1.4% |
| Revenue CAGRlast 5 years | ◎+13.6% | — | +1.6% | — |
| Guidance: revenue growthnext FY plan | ◎+7.5% | +6.6% | +4.4% | +6.6% |
| Guidance: op. profit growthnext FY plan | ◎+6.5% | +3.6% | −16.2% | +5.1% |
| Metric | Rohto | Santen | Kobayashi | Zeria |
|---|---|---|---|---|
| Share price, 1 year | +16.3% | +21.9% | ◎+39.5% | +1.1% |
| Share price, 3 months | +10.3% | −7.6% | ◎+23.6% | −8.9% |
| P/E (trailing)lower = cheaper | — | 15.7x | 144.1x | 10.3x |
| Equity ratio | — | 70.0% | ◎76.6% | 60.4% |
| Share price (close) | ¥2,740 | ¥1,789.5 | ¥7,089 | ¥1,977 |
◎ marks the best value for each metric. Revenue and profit are from the latest full-year earnings release; share prices are closing-price references; P/E = latest close ÷ trailing EPS. For banks and some other financials, revenue means ordinary income.
| Metric | Rohto | Santen | Kobayashi | Zeria |
|---|---|---|---|---|
| Average salary | ¥8.26M | ◎¥9.02M | ¥7.57M | ¥7.99M |
| Starting salary (monthly) | ¥240,000 | ◎¥314,100 | ¥243,760 | ¥288,060 |
| Average tenure | 14.0 yrs | 15.9 yrs | 12.8 yrs | ◎18.0 yrs |
| Average age | 42.3 | 43.8 | 41.0 | 42.7 |
| Employees | 1,753 | 1,884 | 1,665 | 872 |
Average salary is for the reporting (parent) company and is affected by average age and job mix. Holding companies with few employees are left out of the salary comparison.
Close (Oct 30, 2026)
¥2,740+16.3% (1Y)
Rohto +16.3% over 1Y. Compared: Santen +21.9%, Kobayashi +39.5%, Zeria +1.1%.
Reference chart of daily closing prices, not real-time quotes (split-adjusted; weekly closes before the last year). Each line shows the % change from the start of the period. Updated Oct 30, 2026.
Rohto4 segments
Santen1 segments
Kobayashi2 segments
Zeria3 segments
AAverage annual salary from the securities filings: Santen ¥9.02M, Rohto ¥8.26M, Zeria ¥7.99M, Kobayashi ¥7.57M. Santen pays the most. Averages also depend on staff age and job mix, so check the average age too (Rohto 42.3, Santen 43.8, Kobayashi 41.0, Zeria 42.7).
ARevenue in the latest results: Rohto ¥343.7B, Santen ¥291.6B, Kobayashi ¥165.7B, Zeria ¥89.2B. Rohto is the largest by revenue at ¥343.7B, followed by Santen (¥291.6B), Kobayashi (¥165.7B) and Zeria (¥89.2B).
AOperating margins: Santen 16.4%, Zeria 13.9%, Rohto 12.0%, Kobayashi 9.0%. Santen turns the highest share of sales into operating profit.
AShare price change over the past year (closing prices, for reference): Kobayashi +39.5%, Santen +21.9%, Rohto +16.3%, Zeria +1.1%. Kobayashi has risen the most.
Comparing 4 companies (up to 4)
Sources: earnings releases (kessan tanshin), annual securities reports and other public information. Share prices are closing-price references, not real-time. Our data may contain errors; investment decisions are your own responsibility.
