Pharmaceutical Companies Ranked by Operating Margin (FY2026, 23 companies)

1. 1
   
   Chugai451947.6%47.6%¥1.3T−3.2%
2. 2
   
   Shionogi450733.4%33.4%¥499.7B+16.7%
3. 3
   
   Sumitomo Pharma450623.7%23.7%¥453.3B+11.9%
4. 4
   
   Nippon Shinyaku451620.8%20.8%¥170.8B+6.7%
5. 5
   
   Otsuka457819.4%19.4%¥2.5T+43.5%
6. 6
   
   Tsumura454018.3%18.3%¥192.6B+6.9%
7. 7
   
   Astellas450317.9%17.9%¥2.1T+59.3%
8. 7
   
   Ono452817.9%17.9%¥515.8B+20.2%
9. 9
   
   Santen453616.4%16.4%¥291.6B+18.6%
10. 10
    
    Zeria455913.9%13.9%¥89.2B−1.2%
11. 11
    
    Rohto452712.0%12.0%¥343.7B+14.7%
12. 12
    
    Daiichi Sankyo456810.8%10.8%¥2.1T−24.9%
13. 13
    
    Takeda45029.1%9.1%¥4.5T+60.1%
14. 14
    
    Kobayashi49679.0%9.0%¥165.7B+38.3%
15. 15
    
    Towa45538.4%8.4%¥273.7B+24.2%
16. 16
    
    Sawai48877.9%7.9%¥201.7B−9.4%
17. 17
    
    Eisai45235.3%5.3%¥825.4B+10.5%
18. 18
    
    Suzuken99871.5%1.5%¥2.5T+2.3%
19. 19
    
    JCR45521.4%1.4%¥40.3B−9.0%
20. 20
    
    Kaken4521-1.2%-1.2%¥76.9B+4.5%
21. 21
    
    Kissei4547-3.0%-3.0%¥97.4B−5.5%
22. 22
    
    Peptide Dream4587-27.1%-27.1%¥18.5B−28.4%
23. 23
    
    Nxera4565-28.6%-28.6%¥29.6B+60.7%

Shares 1Y is a closing-price reference (vs. about a year earlier).

Revenue and operating profit are from the latest full-year consolidated results. Average salary is for the reporting entity per its annual securities report; pure holding companies with fewer than 50 staff are excluded.