Prices as of 2026/10/30 close
Company comparison · Mid-Tier Pharma & Drug Discovery
Ono is the bigger company, with revenue of ¥515.8B — 3.0x Nippon Shinyaku's ¥170.8B.
Nippon Shinyaku earns more on each yen of sales, with an operating margin of 20.8% — 2.9 points above Ono (17.9%).
Revenue growth in the latest results: Nippon Shinyaku +6.6%, Ono +5.9%. For next year, Nippon Shinyaku guides for the fastest operating profit growth (+7.1%).
Ono pays more on average — ¥10.2M against ¥9.19M at Nippon Shinyaku.
Over the past year the shares moved Ono +26.8%, Nippon Shinyaku +6.8%.
Head-to-head wins16 metrics
One win per metric for the company with the best value. Metrics with no better or worse (P/E, average age, employees) are excluded.
ScaleInvestors
Ono aheadOno 3 : Nippon Shinyaku 0
Revenue: Ono ¥515.8B / Nippon Shinyaku ¥170.8B
ProfitabilityInvestors
Nippon Shinyaku aheadOno 1 : Nippon Shinyaku 2
Operating margin: Ono 17.9% / Nippon Shinyaku 20.8%
GrowthInvestors
Nippon Shinyaku aheadOno 2 : Nippon Shinyaku 3
Revenue growth (YoY): Ono +5.9% / Nippon Shinyaku +6.6%
Stock & balance sheetInvestors
EvenOno 1 : Nippon Shinyaku 1
Share price, 1 year: Ono +26.8% / Nippon Shinyaku +6.8%
Pay & workforceJob seekers
Nippon Shinyaku aheadOno 1 : Nippon Shinyaku 2
Average salary: Ono ¥10.2M / Nippon Shinyaku ¥9.19M
| Metric | Ono | Nippon Shinyaku | Gap |
|---|---|---|---|
| Revenue | ◎¥515.8B | ¥170.8B | 3.0x |
| Operating profit | ◎¥92.2B | ¥35.5B | 2.6x |
| Net income | ◎¥69.8B | ¥29.7B | 2.3x |
| Metric | Ono | Nippon Shinyaku | Gap |
|---|---|---|---|
| Operating margin | 17.9% | ◎20.8% | 2.9pt |
| Net margin | 13.5% | ◎17.4% | 3.9pt |
| Revenue per employee | ◎¥149M | ¥91M | 1.6x |
| Metric | Ono | Nippon Shinyaku | Gap |
|---|---|---|---|
| Revenue growth (YoY) | +5.9% | ◎+6.6% | 0.7pt |
| Operating profit growth (YoY) | ◎+54.4% | +0.1% | 54.3pt |
| Revenue CAGRlast 5 years | ◎+10.8% | +7.0% | 3.8pt |
| Guidance: revenue growthnext FY plan | −11.8% | ◎+17.1% | 28.9pt |
| Guidance: op. profit growthnext FY plan | +1.9% | ◎+7.1% | 5.1pt |
| Metric | Ono | Nippon Shinyaku | Gap |
|---|---|---|---|
| Share price, 1 year | ◎+26.8% | +6.8% | 20.0pt |
| Share price, 3 months | −8.2% | ◎−1.7% | 6.5pt |
| Share price (close) | ¥2,256 | ¥3,436 |
◎ marks the best value for each metric. Revenue and profit are from the latest full-year earnings release; share prices are closing-price references; P/E = latest close ÷ trailing EPS. For banks and some other financials, revenue means ordinary income.
| Metric | Ono | Nippon Shinyaku | Gap |
|---|---|---|---|
| Average salary | ◎¥10.2M | ¥9.19M | ¥0.98M |
| Starting salary (monthly) | ¥273,000 | ◎¥279,000 | ¥6,000 |
| Average tenure | 16.9 yrs | ◎17.2 yrs | 0.3 |
| Average age | 44.2 | 41.4 | 2.8 |
| Employees | 3,464 | 1,876 | 1.8x |
Average salary is for the reporting (parent) company and is affected by average age and job mix. Holding companies with few employees are left out of the salary comparison.
Close (Oct 30, 2026)
¥2,256+26.8% (1Y)
Ono +26.8% over 1Y. Compared: Nippon Shinyaku +6.8%.
Reference chart of daily closing prices, not real-time quotes (split-adjusted; weekly closes before the last year). Each line shows the % change from the start of the period. Updated Oct 30, 2026.
Ono1 segments
Nippon Shinyaku2 segments
AAverage annual salary from the securities filings: Ono ¥10.2M, Nippon Shinyaku ¥9.19M. Ono pays the most. Averages also depend on staff age and job mix, so check the average age too (Ono 44.2, Nippon Shinyaku 41.4).
ARevenue in the latest results: Ono ¥515.8B, Nippon Shinyaku ¥170.8B. Ono is the bigger company, with revenue of ¥515.8B — 3.0x Nippon Shinyaku's ¥170.8B.
AOperating margins: Nippon Shinyaku 20.8%, Ono 17.9%. Nippon Shinyaku turns the highest share of sales into operating profit.
AShare price change over the past year (closing prices, for reference): Ono +26.8%, Nippon Shinyaku +6.8%. Ono has risen the most.


Comparing 2 companies (up to 4)
Sources: earnings releases (kessan tanshin), annual securities reports and other public information. Share prices are closing-price references, not real-time. Our data may contain errors; investment decisions are your own responsibility.