Prices as of 2026/10/30 close
Company comparison · Major Pharmaceuticals
Otsuka is the bigger company, with revenue of ¥2.5T — 1.2x Astellas's ¥2.1T.
Otsuka earns more on each yen of sales, with an operating margin of 19.4% — 1.5 points above Astellas (17.9%).
Revenue growth in the latest results: Astellas +11.9%, Otsuka +6.0%. For next year, Astellas guides for the fastest operating profit growth (+3.2%).
Otsuka pays more on average — ¥10.6M against ¥10.5M at Astellas.
Over the past year the shares moved Astellas +63.2%, Otsuka +48.2%.
Head-to-head wins15 metrics
One win per metric for the company with the best value. Metrics with no better or worse (P/E, average age, employees) are excluded.
ScaleInvestors
Otsuka aheadOtsuka 3 : Astellas 0
Revenue: Otsuka ¥2.5T / Astellas ¥2.1T
ProfitabilityInvestors
Otsuka aheadOtsuka 3 : Astellas 0
Operating margin: Otsuka 19.4% / Astellas 17.9%
GrowthInvestors
Astellas aheadOtsuka 1 : Astellas 4
Revenue growth (YoY): Otsuka +6.0% / Astellas +11.9%
Stock & balance sheetInvestors
Astellas aheadOtsuka 0 : Astellas 2
Share price, 1 year: Otsuka +48.2% / Astellas +63.2%
Pay & workforceJob seekers
EvenOtsuka 1 : Astellas 1
Average salary: Otsuka ¥10.6M / Astellas ¥10.5M
| Metric | Otsuka | Astellas | Gap |
|---|---|---|---|
| Revenue | ◎¥2.5T | ¥2.1T | 1.2x |
| Operating profit | ◎¥479.4B | ¥382.6B | 1.3x |
| Net income | ◎¥363.1B | ¥291.5B | 1.2x |
| Metric | Otsuka | Astellas | Gap |
|---|---|---|---|
| Operating margin | ◎19.4% | 17.9% | 1.5pt |
| Net margin | ◎14.7% | 13.6% | 1.1pt |
| ROE | 12.6% | — | |
| Revenue per employee | ◎¥13.5B | ¥521M | 25.9x |
| Metric | Otsuka | Astellas | Gap |
|---|---|---|---|
| Revenue growth (YoY) | +6.0% | ◎+11.9% | 5.9pt |
| Operating profit growth (YoY) | +48.2% | ◎+832.4% | 784.2pt |
| Revenue CAGRlast 4 years | ◎+13.3% | +11.4% | 1.9pt |
| Guidance: revenue growthnext FY plan | +2.1% | ◎+3.8% | 1.7pt |
| Guidance: op. profit growthnext FY plan | −24.9% | ◎+3.2% | 28.1pt |
| Metric | Otsuka | Astellas | Gap |
|---|---|---|---|
| Share price, 1 year | +48.2% | ◎+63.2% | 15.0pt |
| Share price, 3 months | +6.3% | ◎+12.4% | 6.1pt |
| P/E (trailing)lower = cheaper | 17.5x | — | |
| Equity ratio | 72.3% | — | |
| Share price (close) | ¥12,015 | ¥2,571 |
◎ marks the best value for each metric. Revenue and profit are from the latest full-year earnings release; share prices are closing-price references; P/E = latest close ÷ trailing EPS. For banks and some other financials, revenue means ordinary income.
| Metric | Otsuka | Astellas | Gap |
|---|---|---|---|
| Average salary | ◎¥10.6M | ¥10.5M | ¥0.17M |
| Starting salary (monthly) | — | ¥326,700 | |
| Average tenure | 3.2 yrs | ◎15.7 yrs | 12.5 |
| Average age | 44.4 | 42.3 | 2.1 |
| Employees | 183 | 4,105 | 22.4x |
Average salary is for the reporting (parent) company and is affected by average age and job mix. Holding companies with few employees are left out of the salary comparison.
Close (Oct 30, 2026)
¥12,015+48.2% (1Y)
Otsuka +48.2% over 1Y. Compared: Astellas +63.2%.
Reference chart of daily closing prices, not real-time quotes (split-adjusted; weekly closes before the last year). Each line shows the % change from the start of the period. Updated Oct 30, 2026.
Otsuka4 segments
Astellas3 segments
AAverage annual salary from the securities filings: Otsuka ¥10.6M, Astellas ¥10.5M. Otsuka pays the most. Averages also depend on staff age and job mix, so check the average age too (Otsuka 44.4, Astellas 42.3).
ARevenue in the latest results: Otsuka ¥2.5T, Astellas ¥2.1T. Otsuka is the bigger company, with revenue of ¥2.5T — 1.2x Astellas's ¥2.1T.
AOperating margins: Otsuka 19.4%, Astellas 17.9%. Otsuka turns the highest share of sales into operating profit.
AShare price change over the past year (closing prices, for reference): Astellas +63.2%, Otsuka +48.2%. Astellas has risen the most.


Comparing 2 companies (up to 4)
Sources: earnings releases (kessan tanshin), annual securities reports and other public information. Share prices are closing-price references, not real-time. Our data may contain errors; investment decisions are your own responsibility.