Prices as of 2026/10/30 close
Company comparison · Major Pharmaceuticals
Takeda is the largest by revenue at ¥4.5T, followed by Astellas (¥2.1T), Daiichi Sankyo (¥2.1T) and Kyowa Kirin (¥496.8B).
Astellas has the highest operating margin at 17.9%, 8.8 points above the lowest, Takeda (9.1%).
Revenue growth in the latest results: Daiichi Sankyo +12.6%, Astellas +11.9%, Kyowa Kirin +0.3%, Takeda −1.7%. For next year, Daiichi Sankyo guides for the fastest operating profit growth (+37.5%).
Takeda pays the most on average (¥11.0M), ¥1.10M more than Kyowa Kirin (¥9.94M).
Over the past year the shares moved Astellas +63.2%, Takeda +57.1%, Kyowa Kirin +7.1%, Daiichi Sankyo −28.7%.
Head-to-head wins16 metrics
One win per metric for the company with the best value. Metrics with no better or worse (P/E, average age, employees) are excluded.
ScaleInvestors
Takeda aheadTakeda 2 : Astellas 1 : Daiichi Sankyo 0 : Kyowa Kirin 0
Revenue: Takeda ¥4.5T / Astellas ¥2.1T / Daiichi Sankyo ¥2.1T / Kyowa Kirin ¥496.8B
ProfitabilityInvestors
Astellas aheadTakeda 1 : Astellas 2 : Daiichi Sankyo 0 : Kyowa Kirin 0
Operating margin: Takeda 9.1% / Astellas 17.9% / Daiichi Sankyo 10.8%
GrowthInvestors
Daiichi Sankyo aheadTakeda 0 : Astellas 1 : Daiichi Sankyo 4 : Kyowa Kirin 0
Revenue growth (YoY): Takeda −1.7% / Astellas +11.9% / Daiichi Sankyo +12.6% / Kyowa Kirin +0.3%
Stock & balance sheetInvestors
EvenTakeda 1 : Astellas 1 : Daiichi Sankyo 0 : Kyowa Kirin 0
Share price, 1 year: Takeda +57.1% / Astellas +63.2% / Daiichi Sankyo −28.7% / Kyowa Kirin +7.1%
Pay & workforceJob seekers
Daiichi Sankyo aheadTakeda 1 : Astellas 0 : Daiichi Sankyo 2 : Kyowa Kirin 0
Average salary: Takeda ¥11.0M / Astellas ¥10.5M / Daiichi Sankyo ¥11.0M / Kyowa Kirin ¥9.94M
| Metric | Takeda | Astellas | Daiichi Sankyo | Kyowa Kirin |
|---|---|---|---|---|
| Revenue | ◎¥4.5T | ¥2.1T | ¥2.1T | ¥496.8B |
| Operating profit | ◎¥408.8B | ¥382.6B | ¥229.1B | — |
| Net income | ¥191.8B | ◎¥291.5B | ¥259.9B | ¥67.0B |
| Metric | Takeda | Astellas | Daiichi Sankyo | Kyowa Kirin |
|---|---|---|---|---|
| Operating margin | 9.1% | ◎17.9% | 10.8% | — |
| Net margin | 4.3% | ◎13.6% | 12.2% | 13.5% |
| ROE | — | — | — | 7.7% |
| Revenue per employee | ◎¥937M | ¥521M | ¥265M | ¥124M |
| Metric | Takeda | Astellas | Daiichi Sankyo | Kyowa Kirin |
|---|---|---|---|---|
| Revenue growth (YoY) | −1.7% | +11.9% | ◎+12.6% | +0.3% |
| Operating profit growth (YoY) | +19.3% | ◎+832.4% | −31.0% | — |
| Revenue CAGRlast 5 years | +7.1% | +11.4% | ◎+17.1% | +9.0% |
| Guidance: revenue growthnext FY plan | +3.0% | +3.8% | ◎+7.4% | +4.7% |
| Guidance: op. profit growthnext FY plan | +2.7% | +3.2% | ◎+37.5% | — |
| Metric | Takeda | Astellas | Daiichi Sankyo | Kyowa Kirin |
|---|---|---|---|---|
| Share price, 1 year | +57.1% | ◎+63.2% | −28.7% | +7.1% |
| Share price, 3 months | ◎+16.3% | +12.4% | −4.7% | −7.0% |
| P/E (trailing)lower = cheaper | — | — | — | 19.2x |
| Equity ratio | — | — | — | 80.6% |
| Share price (close) | ¥6,651 | ¥2,571 | ¥2,754 | ¥2,464 |
◎ marks the best value for each metric. Revenue and profit are from the latest full-year earnings release; share prices are closing-price references; P/E = latest close ÷ trailing EPS. For banks and some other financials, revenue means ordinary income.
| Metric | Takeda | Astellas | Daiichi Sankyo | Kyowa Kirin |
|---|---|---|---|---|
| Average salary | ◎¥11.0M | ¥10.5M | ¥11.0M | ¥9.94M |
| Starting salary (monthly) | ¥300,000 | ¥326,700 | ◎¥360,500 | ¥265,000 |
| Average tenure | 14.4 yrs | 15.7 yrs | ◎19.9 yrs | 16.5 yrs |
| Average age | 43.4 | 42.3 | 45.0 | 43.2 |
| Employees | 4,808 | 4,105 | 8,009 | 4,013 |
Average salary is for the reporting (parent) company and is affected by average age and job mix. Holding companies with few employees are left out of the salary comparison.
Close (Oct 30, 2026)
¥6,651+57.1% (1Y)
Takeda +57.1% over 1Y. Compared: Astellas +63.2%, Daiichi Sankyo -28.7%, Kyowa Kirin +7.1%.
Reference chart of daily closing prices, not real-time quotes (split-adjusted; weekly closes before the last year). Each line shows the % change from the start of the period. Updated Oct 30, 2026.
Takeda5 segments
Astellas3 segments
Daiichi Sankyo3 segments
AAverage annual salary from the securities filings: Takeda ¥11.0M, Daiichi Sankyo ¥11.0M, Astellas ¥10.5M, Kyowa Kirin ¥9.94M. Takeda pays the most. Averages also depend on staff age and job mix, so check the average age too (Takeda 43.4, Astellas 42.3, Daiichi Sankyo 45.0, Kyowa Kirin 43.2).
ARevenue in the latest results: Takeda ¥4.5T, Astellas ¥2.1T, Daiichi Sankyo ¥2.1T, Kyowa Kirin ¥496.8B. Takeda is the largest by revenue at ¥4.5T, followed by Astellas (¥2.1T), Daiichi Sankyo (¥2.1T) and Kyowa Kirin (¥496.8B).
AOperating margins: Astellas 17.9%, Daiichi Sankyo 10.8%, Takeda 9.1%. Astellas turns the highest share of sales into operating profit.
AShare price change over the past year (closing prices, for reference): Astellas +63.2%, Takeda +57.1%, Kyowa Kirin +7.1%, Daiichi Sankyo −28.7%. Astellas has risen the most.
Comparing 4 companies (up to 4)
Sources: earnings releases (kessan tanshin), annual securities reports and other public information. Share prices are closing-price references, not real-time. Our data may contain errors; investment decisions are your own responsibility.
